Bone marrow in primary amyloidosis
نویسندگان
چکیده
منابع مشابه
Bone marrow amyloidosis.
A 54-year-old man presented with nephrotic syndrome, renal impairment and restrictive cardiomyopathy. On admission, physical examination revealed pallor, peripheral edema and moderate hepatosplenomegaly. Hematologic values were: Hb 9.7 g/dL, WBC 10.4×10/L with a normal differential count, platelets 109×10/L. Kappa monoclonal light chains were identified by urine immunofixation. Circulating kapp...
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Background: Bone marrow is the site of many malignant disorders and it is one of the common places for solid tumors to metastasize. Examination of the bone marrow aspirate and biopsy is a routine procedure performed for assessment of various conditions such as cytopenias, hematologic neoplasms, nonmalignant disorders and metastatic neoplasms. Methods: The patients were referred to the Hema...
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We describe a patient with primary amyloidosis in whom multiple osteolytic lesions caused by amyloid bone tumours developed, and review the clinical features of the 18 cases with primary amyloidosis in whom destructive bone lesions have been reported. In contrast to amyloidosis associated with multiple myeloma, destructive lesions in the primary disease are mainly located to long bones; joint i...
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In order to classify the underlying disorder in four patients with biopsy-proven amyloidosis without overt monoclonal gammopathy, the cytoplasmic immunoglobulin (Ig) distribution of bone marrow plasma cells was evaluated using direct immunofluorescence microscopy. This procedure revealed the presence of a monoclonal proliferation of light chain containing plasma cells, and thus led to the diagn...
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Background & objective: Introduction: First detection of any solid tumour as metastatic deposits in bone marrow directs clinicians to start searching for the primary tumour. Detection of bone marrow metastasis determines the stage of the malignancy, prognosis, mode of treatment, chemotherapeutic response and follow-up in case of relapse. The aim of the current...
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ژورنال
عنوان ژورنال: American Journal of Hematology
سال: 2005
ISSN: 0361-8609,1096-8652
DOI: 10.1002/ajh.20320